In India, medicine became a separate science very early, according to the sacred books, the Vedas. Notwithstanding this, demonology played a large part in the production of disease according to their theories, and religious observances were helpful in the cures.

Among the oldest documents which we possess relative to the practice of medicine, are the various treatises contained in the collection which bears the name of Hippocrates (460-375 B. C.). He was the first physician to relieve medicine from the trammels of superstition and the delusions of philosophy.

The Greeks undoubtedly believed in demons, but, different from the nations around them, considered the demons to be well-intentioned. Homer (c. 1000 B. C.) speaks frequently of demons, and in one instance in the Odyssey tells of a sick man pining away, "one upon whom a hateful demon had gazed." Empedocles (c. 490-430 B. C.) taught that demons "were of a mixed and inconstant nature, and are subjected to a purgatorial process which may finally end in their ascension to higher abodes." Yet he attributed to them nearly all the calamities, vexations, and plagues incident to mankind. Plato (427-347 B. C.) writes of demons good and bad, and Aristotle (384-322 B. C.), the son of a physician, speaks directly of "demons influencing and inspiring the possessed." Socrates (470-399 B. C.) claimed to have continually with him a demon—a guardian spirit.

In Greece, in early days, physicians were looked upon as gods. Even after the siege of Troy, the sons of the gods and the heroes were alone supposed to understand the secrets of medicine and surgery. At a late period Æsculapius, the son of Apollo, was worshipped as a deity. When we speak of the art of healing in Greece, one naturally thinks of the apparent monopoly of the Æsclepiades, who ministered unto the Grecian sick for centuries.

The original seat of the worship of Æsculapius was at Epidaurus, where there was a splendid temple, adorned with a gold and ivory statue of the god, who was represented sitting, one hand holding a staff, the other resting on the head of a serpent, the emblem of sagacity and longevity; a dog crouched at his feet. The temple was frequented by harmless serpents, in the form of which the god was supposed to manifest himself. According to Homer, his sons, Machaon and Podalirius, who were great warriors, treated wounds and external diseases only; and it is probable that their father practised in the same manner, as he is said to have invented the probe and the bandaging of wounds. His priests, the Æsclepiades, however, practised incantations, and cured diseases by leading their patients to believe that the god himself delivered his prescriptions in dreams and visions; for this imposture they were roughly satirized by Aristophanes in his play of "Plutus." It is probable that the preparations, consisting of abstinence, tranquillity, and bathing, requisite for obtaining the divine intercourse, and, above all, the confidence reposed in the Æsclepiades, were often productive of benefit.

The excavations of Cavvadias at Epidaurus have furnished us with much interesting material concerning the cures performed at this ancient shrine, five hundred years before the beginning of the Christian era. If the modern physician still recognizes Æsculapius as his patron saint, he must have great respect for mental healing. It appears certain from inscriptions found upon "stelæ" that were dug up at Epidaurus and published in 1891, that the system of Æsculapius was based upon the miracle-working of a demi-god, and not upon medical art as we now know it. The modus operandi was unique in some details. The patients, mostly incurables, came laden with sacrifices. After prayer, they cleansed themselves with water from the holy well, and offered up sacrifices. Certain ceremonial acts were then performed by the priests, and the patients were put to sleep on the skins of the animals offered at the altar, or at the foot of the statue of the divinity, while the priests performed further sacred rites. The son of Apollo then appeared to them in dreams, attended to the particular ailments of the sufferers, and specified further sacrifices or acts which would restore health. In many cases the sick awoke suddenly cured. Large sums of money were asked for these cures; from one inscription we learn that a sum corresponding to $12,000 was paid as a fee. The record of the cure was carved on the temple as at Lourdes to-day, e.g.:

"Some days back, a certain Caius, who was blind, learned from an oracle that he should repair to the temple, put up his fervent prayers, cross the sanctuary from right to left, place his five fingers on the altar, then raise his hand and cover his eyes. He obeyed, and instantly his sight was restored, amid the loud acclamations of the multitude. These signs of the omnipotence of the gods were shown in the reign of Antoninus."

"A blind soldier, named Valerius Apes, having consulted the oracle, was informed that he should mix the blood of a white cock with honey, to make up an ointment to be applied to his eyes for three consecutive days. He received his sight, and returned public thanks to the gods."

"Julian appeared lost beyond all hope, from a spitting of blood. The gods ordered him to take from the altar some seeds of the pine, and to mix them with honey, of which mixture he was to eat for three days. He was saved, and came to thank the gods in the presence of the people."2

It was not until five centuries later, when credulity concerning miracles was on the wane, that the priests began to study and to apply medical means in order to sustain the reputation of the place, and to keep up its enormous revenues.

Temples similar to this one at Epidaurus existed at numerous places, among which were Rhodes, Cnidus, Cos, and one was to be found on the banks of the Tiber. The temple at Cos was rich in votive offerings, which generally represented the parts of the body healed, and an account of the method of cure adopted. From these singular clinical records, Hippocrates, a reputed descendant of Æsculapius, is reported to have constructed his treatise on Dietetics.

For a long time after the age of Hercules and the heroic times, invalids in Greece sought relief from their sufferings from these descendants of Æsculapius in the temples of that god, which an enlightened policy had raised on elevated spots, near medicinal springs, and in salubrious vicinities. Those men who pretended in right of birth to hold the gift of curing, finally learned the art of it. The preservation in the temple of the history of those diseases, the cure of which had been sought by them, aided greatly in this happy culmination.

Of Æsculapius himself, it is said that he employed the trumpet to cure sciatica; he claimed that its continued sound made the fibres of the nerves to palpitate, and the pain vanished. In line with this treatment, Democritus affirmed that diseases are capable of being cured by the sound of a flute, when properly played.

Herbs were also used among the Greeks, but almost wholly in the form of charms rather than on account of what we claim now as real medicinal value. For example, great virtues were ascribed to the herb alysson which was pounded and eaten with meat to cure hydrophobia. If suspended in the house, it promoted the health of the inmates and protected both men and cattle from enchantments; when bound in a piece of scarlet flannel round the necks of the latter, it preserved them from all diseases.