cause or causes to which these phenomena are attributable. After a general introduction, he proceeds to enumerate the three degrees of composition, viz.:—

These divisions correspond roughly to the threefold study of structure which we nowadays recognize as chemical, histological, and anatomical.

As examples of Aristotle's method of treatment, his descriptions of blood, the brain, the heart, and the lung may be considered.

Of the blood he says, "What are called fibres are found in the blood of some animals, but not of all. There are none, for instance, in the blood of deer and of roes, and for this reason the blood of such animals as these never coagulates.... Too great an excess of water makes animals timorous.... Such animals, on the other hand, as have thick and abundant fibres in their blood are of a more choleric temperament, and liable to bursts of passion.... Bulls and boars are choleric, for their blood is exceedingly rich in fibres, and the bull's, at any rate, coagulates more rapidly than that of any other animal.... If these fibres are taken out of the blood, the fluid that remains will no longer coagulate."

From these quotations it will be noted that Aristotle attributed the coagulum to the presence of fibres, and in this he anticipated Malpighi's discovery made in the seventeenth century. His remarks on the proportion of coagulum and serum in different animals, which is enlarged upon in the "History of Animals,"[5] harmonize with modern observations. In another of his works[6] he remarks that the blood in certain diseased conditions will not coagulate. This is known to be the case in cholera, certain fevers, asphyxia, etc.; and the fact was probably obtained from Hippocrates. Although Aristotle speaks here of entire absence of coagulation in the blood of the deer and the roe, in the "History of Animals" he admits an imperfect coagulation, for he says, "so that their blood does not coagulate like that of other animals." The animals named are commonly hunted, and it was probably after they had been hunted to death that he examined them. Now, it is generally admitted that coagulation under such circumstances is imperfect and even uncommon. The statement as to the richness in fibres of the blood of bulls and boars has been confirmed by some modern investigations, which have shown that the clot bears a proportion to the strength and ferocity of the animal. The remarks, however, as to the relative rapidity of coagulation would appear to be contradicted by later observations, for Thackrah came to the conclusion that coagulation commenced sooner in small and weak animals than in strong.

Of the brain Aristotle makes the following among other assertions: "Of all parts of the body there is none so cold as the brain.... Of all the fluids of the body it is the one that has the least blood, for, in fact, it has no blood at all in its proper substance.... That it has no continuity with the organs of sense is plain from simple inspection, and still more closely shown by the fact that when it is touched no sensation is produced.... The brain tempers the heat and seething of the heart.... In order that it may not itself be absolutely without heat, blood-vessels from the aorta end in the membrane which surrounds the brain.... Of all animals man has the largest brain in proportion to his size: and it is larger in men than in women. This is because the region of the heart and of the lung is hotter and richer in blood in man than in any other animal; and in men than in women. This again explains why man alone of animals stands erect. For the heat, overcoming any opposite inclination, makes growth take its own line of direction, which is from the centre of the body upwards.... Man again has more sutures in his skull than any other animal, and the male more than the female. The explanation is to be found in the greater size of the brain, which demands free ventilation proportionate to its bulk.... There is no brain in the hinder part of the head.... The brain in all animals that have one is placed in the front part of the head ... because the heart, from which sensation proceeds, is in the front part of the body."

Although it would perhaps be difficult to find anywhere as many errors in as few words, yet it should be observed that Aristotle here shows himself to have been aware of the existence of the membranes of the brain—the pia mater and the dura mater; and elsewhere[7] he says more explicitly, "Two membranes enclose the brain; that about the skull is the stronger; the inner membrane is slighter than the outer one." And further, it should be noted that he describes the latter membrane as a vascular one. The fact of the brain substance being insensible to mechanical irritation was known to Aristotle, and may have been learnt from the practice of Hippocrates. Lastly, it should be remembered that—though this may have been but a lucky guess on Aristotle's part—the relative weight of brain to the entire body has been shown, with few exceptions, to be greater in man than in any other animal.

In describing the heart Aristotle says: "The heart lies about the centre of the body, but rather in its upper than in its lower half, and also more in front than behind.... In man it inclines a little towards the left, so that it may counterbalance the chilliness of that side. It is hollow, to serve for the reception of the blood; while its wall is thick, that it may serve to protect the source of heat. For here, and here alone, in all the viscera, and in fact in all the body, there is blood without blood-vessels, the blood elsewhere being always contained within vessels. The heart is the first of all the parts of the body to be formed, and no sooner is it formed than it contains blood.... For no sooner is the embryo formed than its heart is seen in motion like a living creature, and this before any of the other parts. The heart is abundantly supplied with sinews.... In no animal does the heart contain a bone, certainly in none of those that we ourselves have inspected, with the exception of the horse and a certain kind of ox. In animals of great size the heart has three cavities; in smaller animals it has two; and in all it has at least one."

It will be observed that here Aristotle so correctly describes the position of the human heart as to render it probable that he is speaking from actual inspection; although man is not the only animal in which the heart is turned towards the left. In contrasting the heart with the other viscera he appears to have overlooked the existence of the coronary vessels, and to have imagined that the nutrition of the heart was effected directly by the blood in