of the lower vertebrates, hanging by two peduncles, or strands of nerve fibre, from the thalami, or beds of the optic nerve, is a small rounded or heart-shaped body of about the size of a pea, known as the pineal gland. It is so destitute of any evident function that Descartes, in lack of any more probable explanation of its presence, ascribed to it the noble duty of serving as the seat of the soul. Late research has been more successful in tracking this organ to its lair. It is larger in the embryo than in the adult man, still larger in some lower vertebrates, and in certain lizards has been found to exist as an eye, its parts plainly distinguishable under the microscope. It is placed in the middle of the forehead, between the other eyes, and was no doubt an active organ of vision in some ancient batrachians.

The pineal eye, as it is now named, once useful, long useless, has persisted as a fossil structure through a far extended line of development. No more convincing evidence that man gained his body through descent from the lower animals could be asked for than the survival in the human brain of this wonderfully significant remnant of a formerly useful organ. Like various other vestiges of ancient organs, it is not only useless but detrimental. It occasionally enlarges and becomes the seat of large and complicated tumors, which may cause death by their compression of the brain.

Two other structures common to most of the vertebrate animals exist in man, though they render him little or no service. These are the thymus and thyroid glands, apparently vestigial structures. The thymus gland attains a considerable development in the embryo and shrinks away to the merest vestige in the adult. It begins to form early in the embryo life as an epithelial ingrowth from the throat, and extends from the neck into the chest. It continues to grow after birth, but later begins to shrink and nearly disappears in the adult.

The thyroid gland has a somewhat similar origin, it beginning as an ingrowth from the lower section of the pharynx and extending down to the lower part of the neck. It subsequently loses its connection with the pharynx, and in adult life is a bilobed structure on either side of the windpipe. Like the thymus it is a ductless gland, abundantly supplied with blood-vessels, and possesses a vast number of small cavities, lined with cells and containing an insoluble jelly. So far as appears, both these glands are useless, or nearly so, to man; or if the thyroid performs any useful service it is a minor and obscure one. Such functions as it may have could probably be performed by some of the other organs, while it is positively detrimental as the seat of goitre. This unsightly disease is due to its enlargement, either by a great increase of its blood-vessels or a development of the capsules and increase of their contained jelly. Dr. S. V. Clevenger considers these organs to have had a branchial or respiratory origin, saying that there are many reasons for believing them to be rudimentary gills. Owen says that the thymus appears in vertebrates with the establishment of the lung as the main or exclusive respiratory organ. It is wanting in all fishes, also in the gill-bearing batrachians, siren and proteus. The thyroid appears in fishes, and Gegenbaur believes that it may have been a useful organ to the Tunicata in their former state of existence.

Dr. Clevenger, in the American Naturalist for January, 1884, points out another curious structure in man, whose significance does not seem to have been previously observed. This is a strange and striking fact relating to the formation of the veins. It is well known that these organs possess valves, which permit the free upward flow of the blood toward the heart, but resist its descent through the action of gravity, in this way aiding its return from the extremities. The rule holds good throughout the quadrupeds that the vertical veins possess valves, while they are absent from the horizontal veins, in which they would be of no utility. But the singular fact exists that in the human trunk the valves occur in the horizontal and are absent from the vertical veins. In other words, they exist where they are useless for their apparent purpose and are absent where they would be useful.

The only conclusion that can reasonably be drawn from this strange fact is that we are here dealing with a fossilized structure, a functionless survival. It leads irresistibly to the inference that man has descended from a quadruped ancestor, and that when his body took the upright position the structure of the veins, not being seriously detrimental, remained unchanged. Those which had been vertical became horizontal, and retained their now useless valves; those which had been horizontal became vertical, and remained destitute of valves. The veins of the arms and legs, vertical in both forms, retained their valves.

Dr. Clevenger points out that the intercostal veins, which carry blood almost horizontally backward to the azygos veins and which would run vertically upward in quadrupeds, possess valves. These are not only useless to man, but when he lies upon his back they are an actual hindrance to the free flow of the blood. In like manner, the inferior thyroid veins, whose blood flows into the innominate, are obstructed by valves at the point of junction.

We quote from him as follows: "There are two pairs of valves in the external jugular and one pair in the internal jugular, but in recognition of their uselessness they do not prevent regurgitation of blood nor liquids from passing upward. An apparent anomaly exists in the absence of valves from parts where they are most needed, as in the venæ cavæ, spinal, iliac, hæmorrhoidal, and portal. The azygos veins have imperfect valves. Place men upon 'all fours' and the law governing the presence and absence of valves is at once apparent, applicable, so far as I have been able to ascertain, to all quadrupedal and quadrumanous animals: Dorsal veins are valved; cephalad, ventrad, and caudad veins have no valves."

Of the few exceptions to this rule, he considers the valves of the jugular veins as in process of becoming obsolete, and the rudimentary azygos valves as a recent development. Valves in the hæmorrhoidal veins would be out of place in quadrupeds, but their absence in man is a serious defect in his organization, since the resulting engorgement of blood gives rise to the distressing disease known as piles. The presence of valves would obviate this.

No one can argue that this useless and, to some extent, injurious condition is a designed result of creation. There could not, indeed, be stronger evidence that man has descended from a quadruped ancestor. Dr. Clevenger points out other serious results of the upright position of the body, from which quadrupeds are free. One of these is the liability to inguinal hernia, or rupture, which leads to much suffering and frequent death in man. Prolapsis uteri is another, and a third to which he particularly alludes is difficulty in parturition.

It has been suggested above that the thyroid gland may possibly be of some minor functional importance, and that the thymus is developed in the embryo sufficiently to be functional. As regards the latter, no one is likely to maintain that an act of direct creation would include the production of an organ of some slight and obscure utility to the embryo and useless in later life. The strong probability is that this gland belongs in the same category with other embryonic survivals yet to be pointed out. As regards the seeming function of the thyroid, it may be said that the surviving relic of an ancient functional organ is quite capable of varying in structure and taking upon itself a new function, of minor value, which in its absence